Calcium channels play a key role in the development of diabetes
Researchers at Karolinska Institutet in Sweden have deciphered the diabetogenic role of a certain type of calcium channel in insulin-secreting beta cells. The researchers believe that blockade of these channels could be a potential new treatment strategy for diabetes. The study is published in the scientific journal PNAS. CaV3.1 channels…
Korean Scientists Shed Light on Pancreatic Beta Cell Regeneration
Korean scientists have discovered ways to replicate pancreatic beta cells destroyed by type 1 diabetes, which is usually diagnosed in children, teens, and young adults. Type 1 diabetes is a condition in which the patient’s immune system destroys insulin-making cells in their pancreas. These are called beta cells. The research…
Manufacturing Novel Stem Cell Products To Treat Type 1 Diabetes
The ISLET project, a multi-center collaboration of leading European researchers, aims to develop a manufacturing pipeline for stem cell-based products to treat patients with Type 1 Diabetes. In Type 1 Diabetes a patient’s immune system destroys the beta cells within the islets of Langerhans in the pancreas making a patient…
Unexpected viral behavior linked to type 1 diabetes in high-risk children
Viruses have long been suspected to be involved in the development of type 1 diabetes, an autoimmune disease, but consistent evidence connecting viruses to the condition has been hard to come by. Investigators at the Baylor College of Medicine, the University of South Florida, and other institutions studied samples available…
Type 1 diabetes: A new starting point to delay autoimmune response
Regulatory T cells (Tregs) prevent excessive immune reactions in healthy people. In the development of autoimmune type 1 diabetes, this protection is not sufficiently effective. Researchers at Helmholtz Zentrum München and LMU Munich have now deciphered a mechanism that impairs Treg differentiation and stability. In the study, when researchers inhibited…
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The ‘Most Dangerous Eating Disorder’: Diabulimia in T1D
When I diagnosed 10-year-old Katie with type 1 diabetes (T1D), I told her that her excess weight and diet were unrelated to her diagnosis. But a few months later, her school teacher singled her out for having diabetes in front of the entire class while declaring that the childhood obesity…
FDA approves new closed-loop insulin delivery system for people with Type 1 diabetes
A new software system that will let people with diabetes customize their treatment and automatically adjust their insulin levels was just approved for use by the Food and Drug Administration. It will reach patients in January 2020. The technology, called Control-IQ, is manufactured by Tandem Diabetes Care and connects with…
FDA names Beta Bionics’ pancreas tech a breakthrough device
This is SUPER cool! Good job Beta Bionics! Dive Brief: Boston-based medtech Beta Bionics said Tuesday it received priority review from FDA as part of the Breakthrough Devices Program for its iLet system, which uses mathematical dosing algorithms to automatically control blood sugar levels in people with diabetes. The technology,…
Brain function irregular in children with Type 1 diabetes, study says
he default mode network, which controls the brain at rest, does not switch off in children with Type 1 diabetes when they focus on a task, a study led by Stanford scientists has shown. Dec 9 2019 Children with Type 1 diabetes show subtle but important differences in brain function…
