Measurement of serum apolipoprotein levels in apolipoprotein-defined lipoprotein subclasses (ADLS) may have an important role in predicting vascular complications in type 1 diabetes (T1D), according to the results of a hypothesis-generating prospective study published in the Journal of Lipid Research.
Serum lipids and apolipoproteins concentrations are important biomarkers of cardiovascular disease, and serum apolipoprotein levels, as well as ADLS, may aid in predicting vascular complications in T1D. ADLS analysis defines particles according to their qualitative apolipoprotein complement and divides them into two families. The subclass names reflect the apolipoproteins present on the particle.
The goal of this study was to investigate the association of serum apolipoproteins and ADLS with cardiovascular events in patients with T1D.