There are 537 million people around the world living with diabetes. And that number is growing. When people have Type 1 diabetes, the immune system attacks and destroys the beta cells in the pancreas that make insulin. These cells regulate glucose levels in the blood which the body needs for energy. Blood sugar will continue to […]
Tag: stem
Breakthrough Research Cures Diabetes Type 1 Using Stem Cells
New research, which was led by the assistant professor of medicine and biomedical engineering at Washington University School of Medicine in St. Louis, Jeffrey R. Millman, has recently shown the potential of stem cells in the treatment of type 1 diabetes. More specifically, the researchers looked at how stem cells from humans can be converted […]
Manufacturing Novel Stem Cell Products To Treat Type 1 Diabetes
The ISLET project, a multi-center collaboration of leading European researchers, aims to develop a manufacturing pipeline for stem cell-based products to treat patients with Type 1 Diabetes. In Type 1 Diabetes a patient’s immune system destroys the beta cells within the islets of Langerhans in the pancreas making a patient depend-ent on life-long delivery of […]
Type 1 diabetes: New pancreatic cell transplant system shows promise
Scientists have developed a way to increase the effectiveness of pancreatic islet transplantation, a promising therapy for type 1 diabetes. New findings could make pancreatic islet cell transplants more effective. Immune rejection by the recipient is a major barrier to pancreatic islet transplants from donors becoming routinely available for the treatment of type 1 diabetes. […]
Lian receives ENGINE grant for stem-cell-based diabetes therapy
UNIVERSITY PARK, Pa. — Xiaojun “Lance” Lian, assistant professor of biomedical engineering, was one of three recipients of the College of Engineering’s ENGineering for Innovation & Entrepreneurship (ENGINE) grant for “Small Molecule-Based Definitive Endoderm Kit and Pancreatic Progenitor Kit for Stem Cell Research and Therapy.” The project focuses on differentiating stem cells into pancreatic beta […]
Diabetes-free Donors are Best Source of Stem Cells for Bone Repair in Type 1 Patients
Durham, NC – A groundbreaking study released today in STEM CELLS Translational Medicine shows that the gold standard for obtaining stem cells to use in transplantation therapy – harvesting them from the patient himself – is not the best way to go when attempting to regenerate bone in a person with type 1 diabetes. Type […]
Engineered “Suicide Genes” Safely Grow Beta Cells From Stem Cells
Researchers have been advancing methods to generate insulin-producing beta cells from pluripotent stem cells (PSC) for the clinical treatment of type 1 diabetes (T1D). However, transplantation of these immature cells into patients poses substantial risks, namely the development of tumors (teratomas) and the growth of these stem cells into unwanted cell types. Pluripotent stem cells […]
Major breakthrough in search for cure of Type 1 diabetes, researchers say
Researchers announced Tuesday a major breakthrough in the search for a cure of Type 1 diabetes. In a study published in Nature Cell Biology, researchers at University of California San Francisco said they have, for the first time, transformed human stem cells into mature insulin-producing cells, according to a press release. Replacing these insulin-producing cells, which […]
Stem Cell Breakthrough Is Crucial Step For Potential Type 1 Diabetes Cure
For the first time, scientists have been able to turn human stem cells into fully grown insulin-producing cells. This important breakthrough is seen by the research team as an important step forward to developing a cure for Type 1 diabetes. The findings are reported in Nature Cell Biology. Type 1 diabetes is an autoimmune disease […]
First European study tests pioneering stem cell therapy in people with type 1 diabetes
A group of people with type 1 diabetes have become the first in Europe to receive a pioneering stem cells treatment that could restore blood glucose control. PEC-Direct islet cell replacement therapy (also known as VC-02) has been designed to replace insulin-producing beta cells in people with type 1 diabetes. If the approach developed by […]