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Pro-inflammatory lipids precede Type 1 diabetes onset in mouse model and children
Type 1 diabetes, or T1D, is an autoimmune disease in which the body’s immune cells — led by inflammatory macrophages — attack and destroy the beta cells of the pancreas that produce insulin. Researchers have long tried to unravel the signaling that provokes this attack. One of the less-studied forms…
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Deleting a gene prevents Type 1 diabetes in mice by disguising insulin-producing cells
MADISON, Wis. — Removing a gene from the cells that produce insulin prevents mice from developing Type 1 diabetes by sparing the cells an attack from their own immune system, a new UW-Madison study shows. The cellular sleight-of-hand may suggest ways to prevent Type 1 diabetes in high-risk individuals, as…
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Study shows type 1 diabetes early diagnosis may be possible
A breakthrough discovery could see type 1 diabetes being diagnosed before symptoms kick in which may help with efforts to delay development of the condition, researchers have said. In most cases, type 1 diabetes is usually identified following symptoms such as extreme thirst, excessive urination and tiredness, all of which…
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Cellular sickness linked to type 1 diabetes onset
A UC San Francisco study of human and mouse pancreatic tissue suggests a new origin story for type 1 (T1) diabetes. The findings flip current assumptions about the causes of the disease on their head and demonstrate a promising new preventative strategy that dramatically reduced disease risk in laboratory animals.…
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Immune cells breakthrough could help to delay onset of type 1 diabetes
Fri, 07 Dec 2018 Jack Woodfield A potential breakthrough into delaying the onset of type 1 diabetes has been made by US researchers. A trial involving a subset of immune cells could mean researchers are one step closer to preventing type 1 diabetes. The research, carried out by the Baylor…
