A Type 1 Diabetes Lifestyle Website
Jean Van Rampelbergh PhD, VP Clinical & Regulatory at Imcyse SA, introduces Imotopes™, the innovative new immunotherapy approach causing scientists to rethink Type 1 diabetes and its treatment Severe and chronic autoimmune diseases are some of the most difficult and complex immune system-related diseases to treat. Normally, the immune system guards against bacteria and viruses […]
medwireNews: People with type 1 diabetes should be screened for other autoimmune diseases, a Finnish research team suggests, after finding these individuals particularly vulnerable to additional disorders. The study of more than 4000 Finnish individuals with type 1 diabetes revealed that 22.8% had at least one additional autoimmune disease, with the most prevalent being hypothyroidism, […]
Do the insulin-producing beta cells in the pancreas unwittingly produce a signal that aids their own demise in Type 1 diabetes? That appears to be the case, according to lipid signaling research co-led by Sasanka Ramanadham, Ph.D., professor of cell, developmental and integrative biology at the University of Alabama at Birmingham, and Charles Chalfant, Ph.D., […]
Regulatory T cells (Tregs) prevent excessive immune reactions in healthy people. In the development of autoimmune type 1 diabetes, this protection is not sufficiently effective. Researchers at Helmholtz Zentrum München and LMU Munich have now deciphered a mechanism that impairs Treg differentiation and stability. In the study, when researchers inhibited the molecule that triggers this […]
A drug used to treat breast cancer, neratinib, has the potential to halt the immune system from destroying beta cells in type 1 diabetes, according to German researchers. Neratinib was able to guard the beta cells, which produce insulin in the pancreas, from attack. The JDRF-funded study showed that the treatment enabled the beta cells […]
Researchers Lorenzo Pasquali and Mireia Ramos-Rodríguez have published recently in Nature Genetics the results of a study on the mechanisms that cause an inflammatory response to trigger pancreatic beta-cell death, leading to the onset of Type 1 Diabetes (T1D). L. Pasquali is a Ramon y Cajal researcher at the Josep Carreras Leukaemia Research Institute (IJC), […]
What is type 1.5 diabetes, or Latent Autoimmune Diabetes in Adults? It is a type of diabetes that “straddles” types one and two diabetes. This means that certain aspects are more like type one, whereas other characteristics are more like type two – hence the name. However, currently it’s not classified as a separate type […]
A breakthrough discovery could see type 1 diabetes being diagnosed before symptoms kick in which may help with efforts to delay development of the condition, researchers have said. In most cases, type 1 diabetes is usually identified following symptoms such as extreme thirst, excessive urination and tiredness, all of which are a result of hyperglycemia […]
According to textbooks, cells of the adaptive immune system must be either B cells or T cells—they can’t be both, or anything in between. But proving once again that nature is full of surprises, scientists have now discovered a novel type of lymphocyte in type 1 diabetes patients that combines characteristics of B cells and […]
Researchers at National Jewish Health have identified an elusive trigger of type 1 diabetes. A protein fragment formed in the pancreas activates the immune system’s T cells, leading them to attack and destroy beta cells, which produce insulin. Lack of insulin is a hallmark of type 1 diabetes. The research, published in the April 5, […]