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Type 1 diabetes not due to genetics only but environment also: Lancet
Type 1 diabetes is a chronic, immune-mediated disease characterised by the destruction of insulin-producing cells. Standardised registry data show that type 1 diabetes incidence has increased 3–4% over the past three decades, supporting the role of environmental factors.Scientists and researchers have struggled to identify a direct cause. Many have questioned…
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New genetic discoveries help predict risk for type 1, type 2 diabetes
Researchers continue to discover more each year about the genetic risk factors for type 1 and type 2 diabetes and how those risk factors interact with the environment. Scientists have linked several genetic mutations to diabetes risk, though not everyone with a genetic mutation will go on to develop the…
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Genetic differences help distinguish type 1 diabetes in children from ‘type 1.5’ in adults
Philadelphia, January, 2020–A multi-center team of researchers led by Children’s Hospital of Philadelphia (CHOP) has discovered a genetic signature that could help distinguish an adult-onset form of diabetes sharing many type 1 diabetes (T1D) characteristics from pediatric-onset T1D, opening the door to potentially more straightforward diagnostic tests for the adult…
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Simple genetic test for type 1 diabetes being developed
For many children with type 1 diabetes, a diagnosis only comes after they find themselves hospitalized in life-threatening diabetic ketoacidosis. Researchers in Virginia hope to change that. Scientists at the Center for Public Health Genomics at the University of Virginia in Charlottesville have developed a test that they think may…
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An Experimental Genetic Test Gives Early Warning For Kids At Risk Of Type 1 Diabetes
Nearly half of all children who develop Type 1 diabetes don’t know they have the disease until they end up in the hospital with a condition that puts them at risk of coma or even death. Researchers in Virginia have set out to see if a genetic test for Type…
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Type 1 diabetes: Genetic risk reflected in gut microbiome
New research finds differences in the gut microbiome of children who are at high genetic risk of developing type 1 diabetes. The findings suggest that certain species of bacteria may have a protective effect in autoimmune conditions. Type 1 diabetes is an autoimmune condition that can develop at any age.…