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FDA Approves Fiasp for Children With Diabetes

The FDA has approved insulin aspart injection (Fiasp, Novo Nordisk), 100 U/mL, as a new mealtime option for children with diabetes—the first fast-acting mealtime insulin injection that does not have a pre-meal dosing recommendation. Diabetes is one of the most common chronic conditions of childhood, with nearly 18,000 new cases of type-1 diabetes diagnosed each […]

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Genetic differences help distinguish type 1 diabetes in children from ‘type 1.5’ in adults

Philadelphia, January, 2020–A multi-center team of researchers led by Children’s Hospital of Philadelphia (CHOP) has discovered a genetic signature that could help distinguish an adult-onset form of diabetes sharing many type 1 diabetes (T1D) characteristics from pediatric-onset T1D, opening the door to potentially more straightforward diagnostic tests for the adult condition and improving responses by […]

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Type 1 diabetes: Genetic risk reflected in gut microbiome

New research finds differences in the gut microbiome of children who are at high genetic risk of developing type 1 diabetes. The findings suggest that certain species of bacteria may have a protective effect in autoimmune conditions. Type 1 diabetes is an autoimmune condition that can develop at any age. However, it tends to occur […]

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Parent-child relationship key to reaching HbA1c goals in pediatric type 1 diabetes

Children with type 1 diabetes are less likely to maintain recommended HbA1c targets if they frequently experience turmoil with their parents and other family members, according to findings published in Diabetic Medicine. “The association between diabetes-related family conflict and poor glycemic control regardless of insulin regimen supports the importance of screening for and addressing family […]

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Nighttime insulin requirements greater for young children vs. teens, adults

Children with type 1 diabetes have a greater range of insulin requirements, particularly at night, compared with adolescents and adults with the condition, according to a study of hybrid closed-loop insulin delivery system users. “[This research] helps to understand the challenges parents/guardians have to cope with when managing diabetes of their young offspring,” Roman Hovorka, […]

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Type 1 diabetes: Baby given insulin powder in trial

A mum has volunteered her baby to take part in a medical trial she hopes will protect the youngster from diabetes. Chloe Phippard’s five-month-old daughter Ava will take a daily dose of insulin powder to see if it can prevent children developing the condition. The trial will explore if the immune system can be trained […]