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London research team is one step closer to possibly curing Type 1 diabetes
LONDON, ONT. — They’re called cell pouches; an innovative therapeutic device created by London research lab Sernova, for patients with Type 1 diabetes. “The cell pouch is a device that’s placed deep under the skin and smaller than a business card and can be inserted rapidly,” says Philip Toleikis, president…
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Insulin-Producing Cells May Last Longer in People With Type 1 Diabetes
Key Takeaways Researchers have found that people with Type 1 diabetes may retain beta cells for much longer than previously thought. Healthcare experts say that the study’s findings do not necessarily mean that insulin treatment and beta cell replacement therapy are no longer needed. Researchers are seeking to develop a…
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Could an ‘invisible’ cell transplant treat diabetes?
Type 1 diabetes used to be a death sentence. After a diagnosis, patients were put on a starvation diet. The lucky ones would have a year or two to live. But, thanks to the discovery of insulin in the early 1920s, this is no longer the case. We need insulin…
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Major advancement in islet cell transplantation for treating Type-1 diabetes
A cure for Type-1 diabetes has come closer with the development of a new method for keeping transplanted insulin-producing cells alive and functional in recipients for long periods even when transplanted underneath the skin. A team led by researchers at the Perelman School of Medicine reports the new method, and…
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Researchers Develop Potential Breakthrough in Type 1 Diabetes Treatment
Researchers from the Salk Institute took a major step forward in developing a new insulin-producing pancreatic cell cluster as a potential treatment for type 1 diabetes patients. The pancreatic cell clusters were developed with stem cell technology and were able to avoid detection by the immune system. That means the…
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Full interview: Genprex’s newly licensed type 1 diabetes gene therapy’s potential explained by scientist
Dr George Gittes, Professor of Surgery at the Children’s Hospital of Pittsburgh explains how and why he began working on the gene therapy licensed by Genprex (NASDAQ:GNPX). Dr Gittes says the therapy, currently undergoing pre-clinical studies, has shown data where it caused pancreatic cells to turn into insulin-producing cells. Watch…
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Do Pancreatic Cells Write Their Own Autoimmune Ending?
Do the insulin-producing beta cells in the pancreas unwittingly produce a signal that aids their own demise in Type 1 diabetes? That appears to be the case, according to lipid signaling research co-led by Sasanka Ramanadham, Ph.D., professor of cell, developmental and integrative biology at the University of Alabama at…
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Manufacturing Novel Stem Cell Products To Treat Type 1 Diabetes
The ISLET project, a multi-center collaboration of leading European researchers, aims to develop a manufacturing pipeline for stem cell-based products to treat patients with Type 1 Diabetes. In Type 1 Diabetes a patient’s immune system destroys the beta cells within the islets of Langerhans in the pancreas making a patient…
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Biomarker identified for early beta cell death in Type 1 diabetes
Beta cells in the pancreas produce insulin. Their death is a key feature of Type 1 diabetes, and that loss starts long before diagnosis. However, there has been no straightforward way to measure that early loss. Anath Shalev, M.D., and colleagues at the University of Alabama at Birmingham now have…
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Novel T-cell subset may have a role in development of type 1 diabetes
A study conducted at the University of Eastern Finland demonstrated that a recently described T-cell subset, so-called peripheral T helper cells, may have a role in the development of type 1 diabetes. The frequency of circulating peripheral T helper cells was observed to be increased both in children with recently…
