T1D and Heart Failure Risk: Not Equal Between Sexes

Women and men with diabetes have different degrees of heart risks, researchers reported from a meta-analysis.

Among more than 12 million people analyzed in published studies, women with type 1 diabetes had more than five times the risk for heart failure than in women free of diabetes (risk ratio 5.15, 95% CI 3.43-7.74), reported Toshiaki Ohkuma, PhD, of the University of New South Wales in Australia, and colleagues.

Although men with type 1 diabetes also had a significantly higher risk of heart failure compared with men free of diabetes, its magnitude wasn’t quite as high as for the women (RR 3.47, 95% CI 2.57-4.69), the team wrote in Diabetologia.

Women and men with type 2 diabetes also saw a significantly higher risk for developing heart failure at some point, although this risk was lower than in people with type 1 diabetes. Women with type 2 diabetes had a nearly two times higher risk for heart failure (RR 1.95, 95% CI 1.70-2.22); men had a slightly smaller point estimate for the increased risk (RR 1.74, 95% CI 1.55-1.95).

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