Higher HbA1c, daily insulin injections increase diabetic ketoacidosis risk

LOS ANGELES — Adults with type 1 diabetes and HbA1c levels of at least 9% are more likely to develop diabetic ketoacidosis, or DKA, than those who reach lower targets, according to findings presented at AACE Annual Scientific and Clinical Congress.

“Achieving glycemic control remains a major barrier to the health and well-being of patients with type 1 diabetes. In addition to the known long-term vascular complications of hyperglycemia, patients with the poorest glycemic control are also at the highest risk for DKA,” Carol H. Wysham, MD, FACE, FACP, Endocrine Today Editorial Board member and clinical professor of medicine at the University of Washington Rockwood Clinic/MultiCare Health System in Seattle, told Endocrine Today. “Health care providers should continue to monitor and educate all patients on the risk factors associated with developing DKA, and be vigilant in patients with HbA1c greater than 9%.”

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