Basal Insulin Reduction 90 Minutes Before Exercise Beneficial for Glucose Control, Hypoglycemia Risk in T1D

A 50% to 80% basal rate reduction performed 90 minutes before beginning exercise will improve open-loop glucose control and decrease the risk for hypoglycemia during exercise in individuals with type 1 diabetes, according to results of a study published in Diabetes Care.

Common strategies for reducing hypoglycemia risk in active individuals with type 1 diabetes include increasing carbohydrate intake before or during exercise and/or performing a basal rate reduction before beginning the exercise regimen. Exercise guidelines for open-loop insulin delivery also suggest performing a basal rate reduction at least 60 to 90 minutes before exercising, although there has been limited evidence to substantiate these recommendations. In the current study, researchers sought to determine the best strategy for basal rate reductions to attenuate hypoglycemia in a cohort of 17 individuals (mean age, 31 ± 10 years) with type 1 diabetes using continuous subcutaneous insulin infusion.

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